Okayama University research: Overloading of protein localization triggers cellular defects

Representation of changes in gene expression levels (green: decreased, violet: increased) upon high-level expression of different types of modified green fluorescent proteins (GFPs).  Clusters of genes with specific functional categories are marked by boxes; clearly, high-level expression of modified GFPs leads to defects in cellular functioning.

Source: Okayama University (JAPAN), Public Relations and Information Strategy

(Okayama, 3 March) Researchers at Okayama University report in Scientific Reports how the overloading of protein transport mechanisms affects cell functioning.  Over-expression of different types of target proteins leads to cellular growth defects, and the mechanism for transporting proteins out of a cell nucleus has the lowest over-expression tolerance.

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Inspirational Disabled Racing Driver Nicolas Hamilton, brother of F1 driver Lewis Hamilton, to open 2017 Mobility Roadshow

 

The Mobility Roadshow organised by Goose Live Events on behalf of Mobility Choice, is delighted to announce that racing driver Nicolas Hamilton will be opening the 2017 event at 10am, 1 June. (NAEC Stoneleigh, Warwickshire).

From the 1st to the 3rd June, The Mobility Roadshow incorporating Get Going Live! will provide a unique experience with an atmosphere to match. It is the original hands-on event for consumers looking to maintain or discover independence when living with restricted mobility. The exhibition provides a free, fully accessible opportunity for disabled drivers to test drive the latest adapted vehicles and specialist conversions accompanied by experienced professional drivers. There will also be a vast range of specialist manufacturers showcasing their latest innovations in wheelchairs, mobility scooters, ramps, hoists and so much more. As the guest celebrity for this year, Nicolas Hamilton will officially open the event and welcome the many visitors, of all ages, looking to discover or maintain independent mobility.

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Tokyo Tech research: New model for deep mantle conveyor belt system at the core of the Earth

 

Mantle convection with inefficient mixing. Silica-poor rocks (green) circulate around coherent domains of ancient silica-rich rocks (grey).  Mantle downwellings (subducted slabs, blue) sink, and upwellings (light red) rise, through conduits between these domains. Mantle convection is dominantly driven by heating from the hot core (dark red) below.

Source: Tokyo Institute of Technology, Center for Public Affairs and Communications

For immediate release:  28 February 2017

Tokyo Institute of Technology research: New model for deep mantle conveyor belt system at the core of the Earth

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Tokyo Tech Bulletin: Early cancer intervention with gut bacteria

Tokyo Institute of Technology publishes the latest issue of its online newsletter, Tokyo Tech Bulletin.

(Tokyo, 28 February 2017) Research on energy savings in silicon power transistors, linear programming problems, wearable vibroacoustic devices, turbulent swirling premixed flames, early cancer intervention with gut bacteria, and a Nobel Prize special feature are some of the articles in the February 2017 issue of the Tokyo Institute of Technology Bulletin.

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Goodspeed Roaming available in the newly launched ZTE Blade V8 Lite

  • Goodspeed Roaming embedded in the ZTE Blade V8 Lite
  • With eSIM enabled ecosystem, UROS offers low-cost flat rate data roaming in 120+ countries
  • Provides a simple solution for roaming without bill shock

UROS – Uni-fi Roaming Solutions, the leading global Roaming Solution provider today announces that Goodspeed Roaming will be embedded in the newly launched ZTE Blade V8 Lite. Goodspeed Roaming, offering low-cost flat-rate mobile data globally, is implemented as a joint product development project with ZTE.

“We are delighted to announce that our revered partnership with ZTE has resulted in another new product in the growing Goodspeed Roaming portfolio. With this launch we are aggressively targeting the silent roamer segment, characterized by no usage of mobile services while abroad”, comments UROS Chairman of the Board Jyrki Hallikainen. “Together with ZTE we foresee a strong demand for this product”, he adds.

Goodspeed Roaming provides affordable mobile data connection for those who prefer to keep it simple and eliminate bill shocks. The Goodspeed Roaming App together with the Goodspeed SIM guarantees low-cost connectivity in over 120 countries.

ZTE Blade V8 Lite sales box comes equipped with all the necessary to start enjoying the Goodspeed Roaming service. The Goodspeed Roaming App is embedded in the ZTE Blade V8 Lite and the Goodspeed SIM is ready to be inserted in the dual SIM slot. After activating Goodspeed Roaming in ZTE Blade V8 Lite, the customer can use the Goodspeed SIM by just one tap or switch over to their own home SIM card for data. Customer’s regular number stays available to receive and to make voice calls and to send text messages.

The ZTE Blade V8 Lite with Goodspeed Roaming will be available for purchase from ZTE and UROS sales channels.

Okayama University research: Potential cause of Lafora disease revealed

LB formation is increased by nitric oxide (NO)  Representative images of (a) untreated or (b) NO donor treated wild-type Laforin-expressing cells are shown.  Green, cells stained for Laforin and LB; blue, nuclei. 

Okayama University research: Potential cause of Lafora disease revealed

(Okayama, 27 February) Researchers at Okayama University report in the journal  Matters, a potential third factor in the pathogenesis of Lafora disease.  In addition to gene mutations, chemical modification of the enzyme Laforin induced by nitrosative stress is found to be a likely cause of the illness too.

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